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From the practical point of view, the susceptibility to infection of the guinea pig proved to be the most useful step forward. Today, all... →
I demonstrated the characteristics of experimental fever. It appears after an incubation period which is never less than five days. It follows the... →
Just as the only reservoir for the typhus virus in nature is provided by man, so the only vector of infection is the louse. The bite of the louse is... →
Most of the doctors in the Tunisian administration, especially those in country districts, contracted typhus and approximately one third of them died... →
My first attempts to transmit typhus to laboratory animals, including the smaller species of monkeys, had failed, as had those of my predecessors... →
Of all the problems which were open to me for study, typhus was the most urgent and the most unexplored. We knew nothing of the way in which... →
The discovery that I soon made that the guinea pig was also susceptible to infection made it possible for me, from the third year on, to preserve the... →
The fact that I was fortunate enough to escape contagion, in spite of frequent, sometimes daily contacts with the disease, was because I soon guessed... →
Even if it had not been possible to reproduce the disease in animals and consequently to verify the hypothesis, this simple observation would have... →
At the time when I was conducting my research there was no known method for taking the guinea pig's temperature. I demonstrated a technique which... →
I finally demonstrated that typhus infection is not hereditary in the louse.
It did not seem likely that I was destined to undertake research on typhus.
I was less successful in my attempts to effect preventive vaccination against typhus by using the virus and in trying to produce large quantities of... →